«PHARMACOKINETIC PRINCIPLES. Physicians must learn how to individualize the drug dosage under different conditions to ensure effective and safe therapy. ...» Document abstract
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medical studies
presentation
date published
31/07/2007
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level : General public
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It is generally appreciated that under different conditions a drug may produce diverse effects, ranging from none to a desirable effect or, in other cases, an undesirable, toxic effect. Physicians must learn how to individualize the drug dosage under different conditions to ensure effective and safe therapy.
This requires knowing pharmacokineticsexamining the movement of a drug over time through the bodyand pharmacodynamicsrelating drug concentration to drug effect.
Table of Contents
- PHARMACOKINETIC PRINCIPLES
- ABSORPTION
- FIRST-PASS EFFECT
- BIOAVAILABILITY
- DISTRIBUTION
- VOLUME OF DISTRIBUTION
- ELIMINATION
- Conclusions
« DRUGS WITH PSYCHOACTIVE EFFECTS.. PRINCIPLES OF DRUG THERAPY IN THE ELDERLY.. Discussion. PRINCIPLES OF DRUG THERAPY IN THE ELDERLY. ...» Document abstract
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medical studies
research papers
date published
13/11/2007
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level : Advanced
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The process of aging produces important physiologic changes in the central nervous system, including neuroanatomic, neurotransmitter, and neurophysiologic changes. These processes result in age-related symptoms and manifestations for many older persons. These physiologic changes develop at dramatically variable rates in different older persons, however, the decline being modified by factors such as diet, environment, lifestyle, genetic predisposition, disability, disease, and side effects of drugs. These changes can result in the common age-related symptoms of benign senescence, slowed reaction time, postural hypotension, vertigo or giddiness, presbyopia, presbycusis, stiffened gait, and sleep difficulties. In the absence of disease, these physiologic changes usually result in relatively modest symptoms and little restriction in activities of daily living. These changes decrease physiologic reserve, however, and increase the susceptibility to challenges posed by disease-related, pharmacologic, and environmental stressors.
Table of Contents
- Overview
- MENTAL STATUS EXAMINATION
- FUNCTIONAL ASSESSMENT
- Psychoactive Effects of Drugs in Older Patients
- ADVERSE DRUG EVENTS IN THE ELDERLY.
- DRUGS WITH PSYCHOACTIVE EFFECTS.
- PRINCIPLES OF DRUG THERAPY IN THE ELDERLY.
- Discussion
« FUNCTIONAL ASSESSMENT. ADVERSE DRUG EVENTS IN THE ELDERLY. DRUGS WITH PSYCHOACTIVE EFFECTS. PRINCIPLES OF DRUG THERAPY IN THE ELDERLY. Recommendations. ...» Document abstract
$9.95
medical studies
presentation
date published
31/07/2007
review : not yet assessed
level : General public
requested 1 times
The process of aging produces important physiologic changes in the central nervous system, including neuroanatomic, neurotransmitter, and neurophysiologic changes.
These processes result in age-related symptoms and manifestations for many older persons.
These physiologic changes develop at dramatically variable rates in different older persons, however, the decline being modified by factors such as diet, environment, lifestyle, genetic predisposition, disability, disease, and side effects of drugs.
These changes can result in the common age-related symptoms of benign senescence, slowed reaction time, postural hypotension, vertigo or giddiness, presbyopia, presbycusis, stiffened gait, and sleep difficulties.
Table of Contents
- Overview
- MENTAL STATUS EXAMINATION
- FUNCTIONAL ASSESSMENT
- ADVERSE DRUG EVENTS IN THE ELDERLY
- DRUGS WITH PSYCHOACTIVE EFFECTS
- PRINCIPLES OF DRUG THERAPY IN THE ELDERLY
- Recommendations
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