Structural Explanation of The paradox between High Permeability and High Conductance in a Potassium Channel
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biology
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published 17/09/2007
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SummaryThe human body is a fascinating array of mechanisms, each perfectly sculpted to satisfy its role in the ever changing needs of our physiology. The various systems within us each rely on impulses, sent via the central or peripheral nervous systems, to coordinate everything from breathing to walking to thinking. These messages, sent throughout the entire body and relayed through neurons, consisting of axons and dendrites, are just as intricate as the systems they support.
Table of Contents
- The human body is a fascinating array of mechanisms, each perfectly sculpted to satisfy its role in the ever changing needs of our physiology
- The voltage gated potassium channel through which K+ ions diffuse is shaped somewhat like an 'upside down teepee?.
- Legend: Two of the helical subunits of a voltage gated potassium channel, along with carbonyl binding sites at the top, which is the narrowest region of the channel
- The voltage sensor paddles hold four positive charges, making the total sixteen, which slide almost all the way through the fluid membrane.
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